No part of this publication may be translated into other languages, reproduced or utilized in any form or by any means, electronic or mechanical, including photocopying, recording, microcopying, or by any information storage and retrieval system, without permission in writing from the publisher.ĭrug Dosage: The authors and the publisher have exerted every effort to ensure that drug selection and dosage set forth in this text are in accord with current recommendations and practice at the time of publication. It allows a fast, valid volume calculation in prostate MRI datasets.Ĭopyright: All rights reserved. The ellipsoid formula gives sufficient approximation of prostate volume on 3-Tesla mpMRI without endorectal coil. There was a moderate, significant inverse correlation of prostate volume to a positive biopsy result (r = -0.24, p = 0.004). Volume calculated by the ellipsoid formula showed a strong concordance with planimetric volume, with a tendency to underestimate prostate volume (median volume 43.1 ml (IQR 31.2-58.8 ml) r = 0.903, p < 0.001). The median prostate volume was 48.1 ml (interquartile range (IQR) 36.9-62.1 ml). Planimetric and calculated prostate volumes were compared with clinical data. T2-weighted images were used for measuring the prostate diameters and for planimetric volume measurement by a segmentation software. One hundred forty-three patients with findings on 3-Tesla mpMRI suspicious of cancer and subsequent MRI/US fusion-guided targeted biopsy and additional systematic biopsy were analyzed. We tested the accuracy of the ellipsoid formula with planimetric volume measurements as reference and investigated the correlation of gland volume and cancer detection rate on MRI/ultrasound (MRI/US) fusion-guided biopsy. For 3-Tesla mpMRI without endorectal coil, there is no distinctive standard for volume calculation. Prostate volume in multiparametric MRI (mpMRI) is of clinical importance.
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